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Affiliations
EHIMIGBAI Richard
Department of Anatomy, Faculty of Basic Medical Science, College of Medical Science, University of Benin, Benin City, Edo State
How to Cite
EFFECTS OF LEAD NITRATE ON THE TESTIS OF ADULT WISTAR RATS
Vol 2 No 1 (2016): Volume 2 Number 1
Submitted: Jul 2, 2019
Published: Apr 5, 2016
Abstract
Introduction The aim of this study was aimed at evaluating the effects of lead nitrate on adult wistar rats. Methodology A total of 32 adult wistar rats weighing between 200 and 240g were divided into 4 groups of 8 rats per group. The control groups (group A) were placed on normal diet, while Group B rats received 35mg/ kg body weight / day of lead nitrate via orogastric tube. Group C rats received 45mg / kg body weight/ day of lead nitrate via orogastric tube. Group D rats received 50 mg/ kg body weight/ day of lead nitrate via orogastric tube and all the dosage were given for 40 days.
Results The results in group A, B, C and D showed normal histologic testicular architecture as evidenced by normal seminiferous tubules and interstitial spaces in figure 1, 2, 3 and 4.
Conclusion It was concluded that lead nitrate at 35mg/kg, 45mg/kg and 50mg/kg body weight/day was not toxic to the testis of an adult Wistar rats. Keywords; Lead nitrate, Wistar rat, Histology, Testis